Midlife is the stage in the life of a human being between young adulthood and the onset of old age. It is generally assumed to fall in the bracket of 45 to 65 years of age. This period is characterized by the slowing down of the boy, sensitivity to diet, stress and substance abuse. During midlife, several health conditions may develop like fibroids, migraine and systemic lupus erythematosus. This makes midlife a period warranting attention for gynecologic and hormone-sensitive conditions. Women further experience menopause around the age of 50, which ends their fertility. Over the past decades, studies have advanced the understanding of ovarian aging and its relationship to cardiovascular, bone, cognitive and musculoskeletal health. Signs of aging may become prominent and more rapid in women with osteoporosis. Decline in physical fitness such as reduction in aerobic performance and decrease in maximal heart rate, as well as changes in the skin occur in midlife. Healthy behavior, in particular the maintenance of healthy body weight and physical activity can moderate certain negative changes. Therefore, this period constitutes a critical period for optimizing health and functioning, and preventing chronic diseases. This book is compiled in such a manner, that it will provide in-depth knowledge about women’s midlife health and wellness. It presents researches and studies performed by experts across the globe. It is a vital tool for all researching or studying women’s health as it gives incredible insights into emerging trends and concepts