Microvascular free-flap reconstruction is a surgical procedure that involves the transfer of tissue, along with its blood vessels, from one part of the body to another. This technique is commonly used in reconstructive surgery to repair defects or restore function in areas affected by trauma, cancer, or congenital abnormalities. They can offer the finest biological and biomechanical features, a higher success rate of bone union, at the same instance, the cosmetic and functional score is superior compared to that of non-vascularized flaps, as well as the ability to osseointegrate with dental implants. They are regarded as the gold standard for mandibular reconstruction, especially for those with large or complex defects.