The new edition of this highly respected text explores advances in specific therapeutic approaches and other key information that is otherwise available only through multiple sources. It offers pharmacological, anatomical, and physiological information for basic therapeutic rationales that are not well understood in the field. Widening coverage from the last edition, it includes details on metabolic factors in brain injury, neuroendocrine dysfunction following brain injury, biomechanical assessment of traumatic brain injury, radiologic advances in brain injury, and neuropharmacological and neuropsychological interventions following brain injury.