In this issue of Veterinary Clinics of North America: Equine Practice, guest editor Dr. Megan Romano brings her considerable expertise to the topic of Toxicologic Disorders. Top experts in the field discuss current diagnosis and treatment recommendations for the most common toxicologic causes of disease in equines in North America, including updated information on toxic principles/mechanisms, analytical confirmation, and treatment recommendations. This issue brings more awareness to ABVT-boarded toxicologists and the field, as well.• Contains 15 relevant, practice-oriented topics including postmortem examination in suspected poisoning cases; industrial and agricultural toxicants; mycotoxins; rodenticides; toxic myopathy plants (box elder, white snakeroot, and rayless goldenrod); other toxic plants; and more.• Provides in-depth clinical reviews on toxicologic disorders, offering actionable insights for clinical practice.• Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.