In answering the question of life’s meaning, the African perspective is only just beginning to emerge. While this is true, a critical examination of African theories of meaningfulness, the possibility of life’s meaninglessness, as well as ideas about the proper mode/mood for living with the meaninglessness of life are largely underexplored within the African philosophical tradition. This book provides several plausible accounts of meaning in/of life from an African perspective, examines the relationship between death and life’s meaningfulness, and explores the possibility of life’s meaninglessness, proposing the “philosophy of indifference” as the proper mode/mood for living with the meaninglessness of life.