The authors have compiled into a practical text their experiences encompassing over 20 years of work in the rehabilitation of patients in a persistent vegetative state. In addition to the partial or complete recovery of mental and neurological functions, another condition has been gaining in recognition in recent years: the state of minimal responder, which they elucidate in their book. This title bridges a gap in the specialized literature by providing neurologists, emergency physicians, physiatrists, and internists, as well as therapists, with a new set of tools to aid them in obtaining more rapid progress in the treatment of these patients, whose improvement is wholly dependent upon them.A second equally relevant aspect considered is the relationship of the care-giving physician with the patient's family. Particular attention is given to the approach the physician must take towards family members of the patient lacking mental activity. A third part illustrates the structural and instrumental devices useful in planning and operating a unit specialized in the treatment of patients in the persistent vegetative state, with particular attention given to the rules governing the unit.