The Medici family ruled unofficially and later as dukes the city of Florence and Tuscany, from the end of 14th to the end of the 18th century. Under their patronage the Renaissance was born. The members of this powerful family were able to build their public image in a sophisticated cultural environment where famous artists such as Raphael, Pontormo, Bronzino, Vasari, as well as poets, men of letters, scientists, humanists, were active. Portraits played an important role in this public relations strategy. The portrait types were quite different: from State portraits to family portraits, from those depicting the young heirs of the family name to those of the women that either ruled or played important roles in the dynastic allegiances. In this guide the marvellous works, held in Florence’s Uffizi Gallery and Palazzo Pitti, are presented in chronological order making possible to trace the main stages in the history and genealogy of the Medici family.