Dublin, 1952. When Mary Kate Ryan receives a surprise inheritance from the woman who abandoned her as a tiny baby, she's stunned. All her life, she has longed to know why her mother disappeared, and now she's devastated to realize that every lonely night she spent without a home or family of her own, her mother knew exactly where she was. Mary Kate is about to refuse the money when she sees a beautiful, deserted house for sale and something sparks in her heart. She will reawaken it, as the Dublin Boarding House for Single Ladies, and provide a shelter for others as lost and alone as her. Can she help the two young girls left at the local orphanage, desperate for a home of their own? Or the pregnant teenager on the run, who only wants to keep her baby safe? The boarding house brings Mary Kate love and friendships she never dreamed of, but just as her heart is about to burst with joy, a new guest arrives. The stern older woman won't speak about her past, but when Mary Kate uncovers her story, it reveals a devastating secret about her mother. With her life in turmoil once more, can Mary Kate draw on the strength of the women in the house to help her face her past, or will the tragedy she uncovers spell disaster for them all?