Sepsis and septic shock are global health crises affecting millions of people every year. One person dies every 2.8 seconds due to sepsis and septic shock complications. Twenty percent of all deaths worldwide are associated with sepsis, septic shock and its complications. A delay in detecting and treating sepsis and septic shock increases the risk of mortality. This book simplifies the detection and management of sepsis and septic shock to ensure that this clinical emergency is diagnosed and managed earlier. This septic shock book is composed of chapters that are related to the diagnosis, effects on various organs, and management of sepsis and septic shock. It is well-written by experts from their respective fields and different clinical settings. The chapters are written in simple and understandable language. This book will help increase the awareness of sepsis, and it will be equally helpful to medical and paramedical staff, as well as juniors and experts in the field of the management of sepsis and septic shock.