This book discusses the latest advances in cyber—physical security and resilience of cyber—physical systems, including cyber—attack detection, isolation, situation awareness, resilient estimation and resilient control under attack. It presents both theoretical results and important applications of the methods. Security and Resilience in Cyber—Physical Systems begins by introducing the topic of cyber—physical security, covering state—of—the—art trends in both theory and applications, as well as some of the emerging methodologies and future directions for research. It then moves on to detail theoretical methods of attack detection, resilient estimation and control within cyber—physical systems, before discussing their various applications, such as power generation and distribution, autonomous systems, wireless communication networks and chemical plants. Focusing on the detection of and accommodation to cyber—attacks on cyber—physical systems, and including both estimation and artificial—intelligence—based methods, this book will be of interest to researchers, engineers and graduate students within the fields of cyber—physical security and resilient control.