A young schoolteacher with a serious fear of hospitals must face her worst fears when her boyfriend is injured in a car accident and spirited away to a nightmarish medical center where demons don medical scrubs and nefarious nurses bathe in the blood of their suffering patients. Amy's (
Christine Taylor
) boyfriend has just been involved in a major car accident, but when Amy receives word that her boyfriend has been taken to a hospital that no longer exists, she determines to face her fears and bring her boyfriend back home no matter what horrors await her. Accompanied by a concerned stranger (
Jerry O' Connell
) who remains steadfast in his determination to solve the mystery of St. Rosemary's, Amy is forced to enter a hallucinatory world of soul-shredding terror where nothing is as it seems and unspeakable horrors lie down every dark and lonely hallway.