When Spencer Donovan, a District Attorney for the state of New York, receives a mysterious summons to London regarding her biological family, whom she knows nothing about, she drops everything and catches the next flight out. She's shocked to learn that she may have biological ties to the infamous Jack The Ripper murderer and doesn't believe a word of it, until she realizes that the murders are being repeated verbatim 125 years later and by someone referring to himself as Ripper's Ghost. Spencer works with the history professor who summoned her and a Scotland Yard inspector to try and stop the killer before word spreads across London that Saucy Jack has returned.