This is the tenth volume in the Research Advances series and the seventh published by Plenum Press. Volume 10 is another omnibus volume, providing specialized and advanced reviews in a number of areas related to the use of alcohol, illicit drugs, and tobacco. We include also a brief history of the Center for Alcohol Studies that gives Mark Keller's unique perspective on this noted institution. Two of the chapters are decidedly longer than the others-very long chapters have appeared occasionally in the past, and we think that it is one of the strengths of the series that we are able to accommodate such reviews. Again the editorial board has changed. After several years of service, Reginald G. Smart has stepped down. New to the board are Helen M. Annis, Michael S. Goodstadt, Lynn T. Kozlowski, and Evelyn R. Vingilis. This is likely to be the sole volume for which Goodstadt is on the board, since before completion of this volume he moved from the Addiction Research Foundation to the Center for Alcohol Studies, Rutgers University.