This book focuses on the advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and reproducibility. It also concentrates on the effective applications of these methods that resulted in many discoveries of the role of the proteins expressed in living cells and biological fluids. The book focuses on the description of advantages and disadvantages of each of the commonly used quantitative proteomic methods, and provides concise descriptions of the effective applications of these methods.