Volume I highlights the association of the cellular prion protein (PrP
C
) with copper and zinc, the potential roles of PrP
in Alzheimer’s disease and cancers, insoluble PrP
, PMCA, molecular and cellular mechanisms of PrP
Sc
formation and clearance, possible co-factors involved in the conversion of PrP
into PrP
, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.