Pancreatic ductal adenocarcinoma is the fifth leading cause of cancer death in the USA. Pancreatic cancer develops as a result of the accumulation of genetic and epigenetic alterations in cancercausing genes such as oncogenes and tumorsuppressor genes. The second edition of Pancreatic Cancer: Methods and Prools provides a broad range of prools for molecular, cellular, pathological, and statistical analyses of sporadic and familial pancreatic cancer. It covers topics from invitro cell cultures to invivo mouse models, DNA to protein manipulation, and genetic and epigenetic analyses to treatment development. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, stepbystep, readily reproducible laboratory prools, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, written by highly renowned investigators with expertise in pancreatic cancer, Pancreatic Cancer: Methods and Prools, Second Edition is an invaluable source of proven prools to those who are interested in joining the fight against pancreatic cancer.
Pancreatic ductal adenocarcinoma is the fifth leading cause of cancer death in the USA. Pancreatic cancer develops as a result of the accumulation of genetic and epigenetic alterations in cancercausing genes such as oncogenes and tumorsuppressor genes. The second edition of Pancreatic Cancer: Methods and Prools provides a broad range of prools for molecular, cellular, pathological, and statistical analyses of sporadic and familial pancreatic cancer. It covers topics from invitro cell cultures to invivo mouse models, DNA to protein manipulation, and genetic and epigenetic analyses to treatment development. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, stepbystep, readily reproducible laboratory prools, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, written by highly renowned investigators with expertise in pancreatic cancer, Pancreatic Cancer: Methods and Prools, Second Edition is an invaluable source of proven prools to those who are interested in joining the fight against pancreatic cancer.
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