Authors from across the globe have illustrated developments in the neoadjuvant chemotherapeutic management of several tumor types in this outstanding book. On the basis of the comprehensive experience with this management concept, elaborative information is devoted to the application of this therapy for breast cancer treatment. The book also describes the administration of this therapy on non-breast malignancies. The aim of this book is to provide an extensive comprehension of the rationale supporting neoadjuvant chemotherapy, the present data related to its use based on evidence, restrictions of its approach, and necessary future investigative endeavors to understand the procedure of optimization of the benefits of this innovative management concept.