Two nations, Azuria and Vermeil, are on the brink of ruin as a crystal encroachment spreads across the land. A mysterious egg hatches two Skyscale Rathalos, legendary monsters tied to a prophecy of destruction from a war that took place 200 years ago. Players take on the role of the heir to Azuria, the kingdom’s sole Rathalos Rider and leader of the Rangers. Along with Princess Eleanor of Vermail and her Monstie Anjanath, they journey into forbidden lands to uncover the truth and stop the approaching catastrophe.