This book constitutes the refereed proceedings of the 13th International Conference on Mobile Web and Intelligent Information Systems, MobiWIS 2016, held in Vienna, Austria, in August 2016. The 36 papers presented in this volume were carefully reviewed and selected from 98 submissions. They were organization in topical sections named: mobile Web - practice and experience; advanced Web and mobile systems; security of mobile applications; mobile and wireless networking; mobile applications and wearable devices; mobile Web and applications; personalization and social networks.