Interest in biofilms has increased dramatically in recent years. New microscopic and molecular techniques have revolutionized our understanding of biofilm structure, composition, organization, and activities. This book brings advances in the prevention and treatment of biofilm-related diseases to the attention of clinicians and medical researchers. Human tissues often support complex microbial communities growing as biofilms that can cause infections. As microbes in biofilms exhibit increased tolerance toward anti-microbial agents and decreased susceptibility to host defense systems, biofilm-associated diseases have become increasingly difficult to treat.