This book includes 46 scientific papers presented at the conference and reflecting the latest research in the fields of data mining, machine learning and decision-making. The international scientific conference “Intellectual Systems of Decision-Making and Problems of Computational Intelligence” was held in the Kherson region, Ukraine, from May 25 to 29, 2020. The papers are divided into three sections: “Analysis and Modeling of Complex Systems and Processes,” “Theoretical and Applied Aspects of Decision-Making Systems” and “Computational Intelligence and Inductive Modeling.” The book will be of interest to scientists and developers specialized in the fields of data mining, machine learning and decision-making systems.