This book presents peer-reviewed research from ISBCom 2025 that bridges intelligent systems, blockchain, communication, and data technologies to address real-world challenges. Contributions span advanced AI models for pattern recognition, NLP, computer vision, robotics, and sustainable transportation; blockchain solutions for health care, finance, identity, IoT security, and supply chains; as well as breakthroughs in 5G/6G networks, edge computing, cybersecurity, and quantum communication. Readers will also find innovative work on metaheuristics for large-scale optimization, cloud and big-data frameworks for smart cities, and applications of technology in cultural and social sciences. Designed for academics, engineers, and industry leaders, the book offers practical methods, case studies, and frameworks to guide research, teaching, and development of next-generation intelligent and decentralized technologies.