Renowned as the essential reference for all venous specialists, phlebologists, vascular surgeons, and vascular medicine physicians, the fifth edition of the Handbook of Venous and Lymphatic Disorders: Guidelines of the American Venous Forum covers the investigation, prevention, evaluation, and treatment of venous and lymphatic disorders.The full spectrum of acute and chronic venous disorders, chronic lymphedema and chylous complications are included. New or entirely revised chapters discuss in detail basic considerations, diagnostic evaluation, management of acute venous thrombosis, and chronic venous disorders, including deep venous disease and venous ulcers. Medical treatments, including compression therapy, veno-active compounds, and new oral antithrombotic medications, are discussed. Minimally invasive endovascular techniques to treat deep vein thrombosis and pulmonary embolism with catheter-directed thrombolysis, pharmaco-mechanical, mechanical thrombectomy, and venous stenting are presented.Few areas in medicine have progressed as fast as minimally invasive outpatient treatment of chronic venous disease. Endovenous therapies include laser and radiofrequency ablation, liquid and foam sclerotherapy, minimally invasive surgery, cyanoacrylate embolization, mechanico-chemical or ultrasonic ablations, among others.Written by the world’s foremost venous experts, leaders of the American Venous Forum, and international authorities, the Handbook has become the most important reference for both day-to-day management and investigation of venous and lymphatic disorders.