In this issue of Orthopedic Clinics, guest editors from the esteemed Campbell Clinic bring their considerable expertise to the topic of Evidence-Based Medicine. By systematically reviewing and applying findings from high-quality studies, orthopedic specialists can make more informed choices regarding treatment options, surgical interventions, and postoperative care—including decision making for complex cases such as mangled lower extremities, and other key topics in the field.- Contains 11 relevant, practice-oriented topics including evidence-based advances in improving hip stability in THR; preoperative patient optimizations to reduce complications following TKA; evidence-based decision making in geriatric proximal humerus fractures; evidence-based medicine of vertebral body tethering; using evidence-based guidelines to assess athletes' readiness for return to sport following shoulder stabilization; and more- Provides in-depth clinical reviews on evidence-based medicine, offering actionable insights for clinical practice- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews