In the fourth installment of the Zombie Crusade series, Jack Smith's Indiana settlement has become a target for General Matthew Barnes and his vast army of ever-evolving "hunters." Jack and the other leaders of the resistance decide to go on the offensive, first by travelling south to destroy bridges along the Ohio River. Will full support from the confederation in Utah, as well as valuable new allies, Jack's forces devise a nearly-suicidal plan to eliminate Barnes' main army of monsters by luring the mad general to a decisive battle at historic Vicksburg. As the fighting escalates, David is torn about the need to divulge an explosive family secret that could change the lives of Jack and Luke forever when forever might not last much longer than twenty-four hours. Back in the Midwest, Father O'Brien scours parts of the Great Lakes for potential hideaways in case Barnes can't be stopped, and he begins to befriend a group of wary Canadians on an island in Lake Huron. Meanwhile, Doc Redders makes a startling discovery about the virus that turns ordinary people into flesh-eating monsters.