Devoid of purpose and suffering a loss of faith after the death of his infant son, tabloid journalist and diehard skeptic Eric Demeter will spare no one's feelings in refuting their belief in things otherworldly. But while working to debunk an alleged connection between unusual petroglyphs and UFO sightings on the Navajo reservation of Northeastern Arizona, Eric is attacked by a Skinwalker, a Navajo necromancer with the power to assume animal forms and manipulate physical laws. Thrust into a string of strange happenings and eerie visions, Eric struggles to accept the reality of the world around him. When Spider Woman of Navajo and Hopi creation mythologies appears before Eric to send him on an odyssey to preserve the Four Corners region from cataclysmic Earth changes, he is reluctantly transformed into the prophet needed to guide human survivors to correct the mistakes of history and defend the Earth from the sinister, supernatural force that has plagued mankind since time immemorial.