This fourth edition reflects the most recent technical advances in DNAprotein interaction research. With fully updated chapters that describe techniques proven by their continuous value, the volume also many new chapters have been added that mostly deal with largerscale experiments, reflecting recent advances in "big biology", combining to offer a very useful compendium of prools allowing readers to delve into the intricacies of proteinDNA interaction at levels ranging from the very small (as in the case of singlemolecule FRET) to the very complex (as with circular chromatin conformation capture or 4C). Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, stepbystep, readily reproducible laboratory prools and tips on troubleshooting and avoiding known pitfalls. Authoritative and uptodate, DNAProtein Interactions: Principles and Prools, Fourth Edition will aid researchers in continuing the incredible progress made in this vital area of study.
This fourth edition reflects the most recent technical advances in DNAprotein interaction research. With fully updated chapters that describe techniques proven by their continuous value, the volume also many new chapters have been added that mostly deal with largerscale experiments, reflecting recent advances in "big biology", combining to offer a very useful compendium of prools allowing readers to delve into the intricacies of proteinDNA interaction at levels ranging from the very small (as in the case of singlemolecule FRET) to the very complex (as with circular chromatin conformation capture or 4C). Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, stepbystep, readily reproducible laboratory prools and tips on troubleshooting and avoiding known pitfalls. Authoritative and uptodate, DNAProtein Interactions: Principles and Prools, Fourth Edition will aid researchers in continuing the incredible progress made in this vital area of study.
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