Disorders of neuronal migration can cause learning disability, autism, and epilepsy. Many are genetically determined and need precise diagnosis to provide genetic counselling. This book will help the clinician to acquire insight as well as proficiency in diagnosis. Individual chapters describe subgroups including lissencephalies, subependymal heterotopia, non-lissencephalic cortical dysplasias, anomalies of the corpus callosum, hemimegalencephaly, schizencephaly, polymicrogyria and multisystem disorders with impaired migration such as chromosomal and metabolic syndromes. Neuroradiological and genetic data are provided with the respective chapters. Although the book is intended for clinical practice, it provides core information for all interested in this important biological process.
Disorders of neuronal migration can cause learning disability, autism, and epilepsy. Many are genetically determined and need precise diagnosis to provide genetic counselling. This book will help the clinician to acquire insight as well as proficiency in diagnosis. Individual chapters describe subgroups including lissencephalies, subependymal heterotopia, non-lissencephalic cortical dysplasias, anomalies of the corpus callosum, hemimegalencephaly, schizencephaly, polymicrogyria and multisystem disorders with impaired migration such as chromosomal and metabolic syndromes. Neuroradiological and genetic data are provided with the respective chapters. Although the book is intended for clinical practice, it provides core information for all interested in this important biological process.
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