The average duration of Active Shooter incidents in Institutions of Higher Education within the United States is 12.5 minutes. In contrast, the average response time of campus and local law enforcement to these incidents is 18 minutes. In the majority of Active Shooter incidents affecting U.S. IHEs, the emergency response time greatly exceeds the incident duration and affords law enforcement authorities no opportunity to interdict the shooter or prevent further casualties. This stark contrast between response requirements and response capability produces a considerable delta of dead, injured or potential victims and provides the unfortunate motivation for this project. The primary focus of this project is aimed at reducing the Rate of Kill of Active Shooters in U.S. IHEs. This book contains 14 case studies that examine lethal Active Shooter incidents that occurred in U.S. IHEs, as well as the Oslo and Utoya Island Active Shooter event that occurred in Norway. Data analysis on each of these incidents revealed facility composition as a critical vulnerability common to all of these incidents. Accordingly, the recommendations included in this thesis suggest a practical implementation of facility upgrades capable of mitigating the deadly effects of Active Shooters.