This book is intended primarily for researchers, engineers, and graduate students in the fields of medicine management and software engineering in the field of dermatology. Aiming at the problems of color deviation, structured noise interference, and uneven distribution of feature points in the identification of melanoma, this book researches four aspects of dermoscopic image such as color correction, hair removal, image registration and classification recognition. Some creative methods are presented as follows, 1 Dermoscopic image color correction, 2 Dermoscopic image hair removal, 3 Dermoscopic image registration. In writing style, a combination of diagrams, tables, formula and text is used in order that the book can be understood easily and raise the readers’ interest, and in content, theoretical analysis and medical application are combined to describe the advanced technologies in every chapter.