Cardiac nuclear medicine has grown dramatically over the past decade to the point where it is now an integral part of the routine diagnostic workup in patients with heart disease, particularly coro- nary artery disease. In no small part, this is the result of dramatic improvements in technology and the application of these improve- of diagnostic techniques. ments to the development and refinement In this book, authorities on cardiac imaging techniques provide an up-to-date description of the field, covering the clinical appli- cability, efficacy, and future potential of myocardial perfusion scinti- graphy, quantitation of regional blood flow, assessment of ventricu- lar performance, and detection of acute infarction using radio- tracers. This book provides the physician involved in cardiac diag- nosis with the background necessary to integrate the radiotracer method into his diagnostic armamentarium. Boston, August 1979 B.L. HOLMAN Contents Cardiac Nuclear Medicine: An Overview By B.L. HOLMAN . . . . . . . . . . . 1 Assessment of Ventricular Function with First-Pass Angio- cardiography By N. ScHAD and 0. NICKEL With 7 Figures . . . . . . . . . . . . . . . . . . . . . 9 Equilibrium (Gated) Radionuclide Ventriculography By W.E. ADAM, A. TARKOWSKA, F. BITTER, M. STAUCH, and H. GEFFERS With 15 Figures . . . . . . . . . . . . . . . . 21 . . . . Myocardial Scintigraphy with Infarct-Avid Tracers By B.L. HOLMAN and J. WYNNE With 3 Figures . . . . . . . . . . . . . . . . 35 . . . . Quantitative Assessment of Thallium-201 Images By U. BuELL, E. KLEINHANS, M. SEIDERER, and B.E. STRADER With 10 Figures . . . . . . . . . . . . . . . . 43 . . . . Thallium-201 Myocardial Perfusion Scintigraphy during Rest and Exercise By A. LENAERS . . . . . . . . . . . . . . . . . 55 . . . .