The explosive growth of bioeconomy and bioscience, coupled with an interconnected planet increases the potential impact of large-scale bio-events. Either causing public health threats as in epidemics or posing food security issues, from mass poisonings to large-scale starvation, such eventualities are direct threats and indirect destabilizers in a planetary context. The issue of Biosecurity thus pervades every affected aspect, from exploitations of the agro-sector and the food industry to the Public Health management, the novel therapeutic/treatment approaches, the new age of space, deep-sea and subterranean explorations and the interface with the cyber world and the massive or small-scale projection of violence. It has been present since ancient times tacitly and discreetly but only recently took its present guise, the different aspects of which are explored in this book.