This book Artificial Intelligence in Healthcare: Revolutionizing Diagnosis and Treatment deals with recent breakthroughs in the application of AI in healthcare. We illuminate a roadmap designed to construct AI systems that are not only effective but also reliable and safe. The discussion extends to the potential future trajectories of AI-augmented healthcare systems, shedding light on the transformative journey that lies ahead. The spotlight is on the seismic shift enabled by technology and AI, which holds the promise of alleviating the strain on healthcare systems grappling with a multitude of challenges. The availability of diverse data types, from the molecular level to socio-economic factors, provides a comprehensive understanding of health determinants. Meanwhile, advancements in mobile technology and IoT facilitate remote monitoring and personalized interventions, enhancing both preventive and curative aspects of healthcare.