Liz, Frank, and Sonia arrive at Dillon's Island, in the Florida Keys. They're welcomed by Rell, Dillon's close friend and caretaker for the island. Shaken up by the loss of Jill and Dillon, they are ill prepared for the looming threat of Summerfield. This sinister corporation provokes them into an all out war. The streets of New Orleans are bathed in blood as the first decisive battle rages. New mutants threaten to destroy both sides as they assume their dominion over the world. What can they hope to win at the end of the world? Secrets are revealed while more questions are asked than solved.