The modern world and its advances have progressively contributed to the rise of chronic degenerative diseases, especially cancer. The World Health Organisation characterises neoplasia affecting the oral cavity as the most frequent in the head/neck region. One of the best ways to combat oral cancer is prevention. Natural products, including propolis, are rich in bioactive compounds and represent a good chemoprotective alternative, with possible antitumour activity. Thus, this book aims to investigate the antitumour and chemopreventive effect of oral administration of the hydroalcoholic extract of Brazilian Red Propolis. The aim is to identify other compounds with potential for future product development and research that will provide new sources of knowledge for researchers in the fields of phytotherapy, oncology, and other areas of health. These compounds may act as adjuvant agents in the prevention of oral cancer, and Brazilian Red Propolis from Sergipe has been studied in this book for its various biological actions.