This book provides comprehensive insights into affective disorders which are also known as mood disorders. The origin, progression and consequences of disorders are determined by the interplay of psychological, social and cultural factors along with biochemistry and physiology. This book discusses and presents recent reports on synchronization between brain and its cognitive processes and gives supporting evidence to the fact that biochemistry and physiology hold a strong link with our everyday events. It has been composed from the reports by experts on affective disorders and deals with diagnosis, neurobiology and early life stress associated with Mood Disorders. It talks about challenges and problems that affective disorder patients face, and it also presents research and treatment methods to cure these disorders. The content is easy to understand and highly accessible to researchers, doctors and medical students.